HL Deb 08 July 2003 vol 651 c36WA
Lord Clement-Jones

asked Her Majesty's Government:

Why previously untransfused males are perceived as the safest possible blood donors with respect to transfusion-related acute lung injury (TRALI) when a product, widely used in other countries, which can eliminate the risk of TRALI is commercially available. [HL3489]

Lord Warner

The Government's Advisory Committee on the Microbiological Safety of Blood and Tissue for Transplantation have considered the relative efficacy and risks of the different types of fresh frozen plasma (FFP) available.

Occasionally, FFP causes a rare condition called transfusion-related lung injury. This can happen if the donor plasma contains antibodies that can react with the patient's white blood cell. Donors generally produce these antibodies after pregnancy or transfusion. The National Blood Service (NBS) is considering plans to produce FFP from male donors.

There are two types of FFP available to the National Health Service. Clinicians have a choice of which products to use. United Kingdom sourced single unit FFP available from the NBS is more commonly used by the NHS. Each unit of FFP available from the NBS is made from plasma from single donations from donors who have been previously tested for viruses to minimise the risk of infection.