The Department recognises the importance of the pre-exposure prophylaxis (PrEP) impact trial. NHS England has announced it supports expansion of the trial and we are actively considering the next steps in relation to PrEP. The Department has not made any assessment of the number of people that will be infected with HIV as a result of being unable to access the trial. Where centres are closed to recruitment there are arrangements in place to re-direct people to other trial centres.