There are over 70 hormone replacement therapy (HRT) products available in the United Kingdom and while most remain in good supply, a range of factors including an increase in demand has led to issues with a limited number of products. There are currently Serious Shortage Protocols (SSP) in place for Sandrena gel, Lenzetto spray and Estraderm MX 75 microgram patches. We are aware of ongoing supply issues with these products and have extended the SSP