Cattle that test positive for TB must be isolated from the herd and are rapidly removed. In 2021, a total of 27,855 cattle were slaughtered for TB disease control purposes in England. The vast majority (94%) of these cattle had a positive result to a TB test, the remaining 6% were considered direct contacts or had 2 inconclusive results and compulsory slaughtered. Visible lesions were found, through post-mortem examination, in 4,869 (18.7%) of the 26,105 TB test positive animals identified in 2021. The absence of visible lesions of TB at post-mortem examination of test positive cattle does not indicate absence of infection.