The Human Fertilisation and Embryology Authority (HFEA) has advised that the 2011, 2013, and 2014 reports: Scientific review of the safety and efficacy of methods to avoid mitochondrial disease through assisted conception have not found evidence that use of pronuclear transfer (PNT) or maternal spindle transfer (MST) results in abnormalities. However, the HFEA would expect that the health of all babies born following PNT and MST would be assessed at birth and in long term follow-up studies and that these assessments would identify any abnormalities where they are present. The Human Fertilisation and Embryology (Mitochondrial Donation) Regulations 2015 will not come into force until 29 October 2015. The HFEA will announce its proposals for the regulation, monitoring and reporting of mitochondrial donation treatment cycles in due course.