<p>The assessment of the efficacy of smoking cessation products and approaches are presented in the evidence review for the National Institute for Health and Care Excellence (NICE) guideline ‘Tobacco: preventing uptake, promoting quitting and treating dependence’ published 30 November 2021 available at the following link:</p><p><a href="https://www.nice.org.uk/guidance/ng209/evidence/evidence-reviews-11188110061?tab=evidence" target="_blank">https://www.nice.org.uk/guidance/ng209/evidence/evidence-reviews-11188110061?tab=evidence</a></p><p>Through the National Institute for Health and Care Research (NIHR), the Department regularly commissions research into the efficacy of smoking cessation products and approaches. Active NIHR projects include:</p><p>- Effectiveness of Electronic Cigarettes compared with combination nicotine replacement therapy for smoking cessation in patients with chronic obstructive pulmonary disease And effect on Lung health (ECAL study);</p><p>- Effects of e-cigarettes vs usual care for smoking cessation when offered at homeless centres: A cluster randomised controlled trial;</p><p>- Cessation of Smoking Trial in the Emergency Department (CoSTED); and</p><p>- Do e-cigarettes help smokers quit when not accompanied by intensive behavioural support?</p><p> </p><p>The NIHR is also the largest funder of the Cochrane Tobacco Addiction Group which conducts systematic reviews of the evidence on interventions to prevent and treat tobacco addiction.</p>