<p>The Home Office takes non-compliance with the Animals (Scientific Procedures) Act 1986 very seriously. The numbers of non-compliance cases vary in any given year. In 2022 the Animals in Science Regulation Unit introduced improvements in how non-compliance is reported, which includes self-reporting. The self-reporting of non-compliance by establishments is vital to assure a culture of compliance. The increase in numbers of reported non-compliances in the annual report was driven by increased self-reporting.</p><p>The Animals in Science Regulation Unit will further evaluate trends in non-compliance as its regulatory reform programme develops. Every case is investigated, and remedies and sanctions applied according to its published non-compliance policy.</p>