Developing a vaccine against TB in cattle is one of the Government’s top priorities. Defra aims to have a deployable cattle TB vaccine (‘CattleBCG’) and a new companion DIVA skin test (to detect infected among vaccinated animals) in the next few years. Field trials of the CattleBCG vaccine and the DIVA skin test started in 2021 and are ongoing. Final deployment will rely on the success of the ongoing field trials, achieving UK Marketing Authorisations from the Veterinary Medicines Directorate (VMD) (for both CattleBCG and the companion DIVA skin test), gaining international recognition through WOAH and our trading partners for both products, an IT system to record and trace vaccinated cattle, and acceptance of vaccination from stakeholders across the supply chain. Defra is working closely with industry to co-design policy proposals that will be brought to public consultation. This would pave the way for removing or relaxing legal barriers to CattleBCG and DIVA skin test use in England and Wales.