§ Mr. Simon HughesTo ask the Secretary of State for Health if he will list for the last five years for which information is available the serious adverse reactions to vaccines containing components against mumps, measles or rubella; if he will list the trial products which have been withdrawn; and if he will make a statement. [80035]
§ Ms JowellDrug Analysis Prints, listing all serious suspected reactions reported to the Committee on Safety of Medicines between 1 January 1994 and 31 December 1998 for vaccines containing components against mumps, measles or rubella, have been placed in the Library along with an information sheet to aid interpretation.
There have been no trial products withdrawn or licences for these vaccines suspended or revoked in the last five years.
§ Mr. Simon HughesTo ask the Secretary of State for Health if he will list each of the years since 1969 in which vaccinations or revised vaccinations were introduced for mumps, measles and rubella. [80032]
§ Ms JowellMeasles vaccine for infants was introduced into the United Kingdom immunisation programme in 1968. Rubella immunisation was introduced in 1970 for girls aged 10 to 14 and non-immune women. Single antigen mumps vaccine has never been a part of the United Kingdom's immunisation programme. Measles, mumps and rubella (MMR) vaccine for children aged 12 to 15 months was introduced in October 1988; this replaced single antigen measles vaccine. Routine rubella immunisation for girls aged 10 to 14 was discontinued in October 1995. A second dose of MMR vaccine at pre-school entry was introduced in October 1996. In addition, a special, one-off immunisation campaign of children aged 5 to 16 was conducted in November 1994 with measles/rubella vaccine to avert a measles epidemic.
§ Mr. Simon HughesTo ask the Secretary of State for Health if he will list vaccines licensed since 1 February 1987 for mumps, measles and rubella, or a combination 111W of these, indicating for each product (a) the date on which a licence was granted, (b) the conditions for which it was licensed and (c) if the product licence is current. [80036]
Product Name Date of Grant Pluserix MMR Vaccine Injection with Diluent1 17 June 1988 Rubavax Rubella Live Vaccine1 18 September 1989 Measavax Vaccine Injection1 18 September 1989 Immravax Measles Mumps Rubella Live Attenuated Vaccine Injection1 18 September 1989 Rubilin - Rubella Vaccine Live BP 28 February 1992 Immravax/Measles, Mumps and Rubella Vaccine Live BP 18 October 1993 Rimevax Measles Vaccine 25 October 1993 Mevilin-L Measles Vaccine Live BP 6 January 1994 Eolarix Vaccine Injection 22 July 1994 Merieux Measles and Rubella Vaccine Injection I September 1994 Measavax Vaccine 1000TC1D50/Dose 13 October 1994 Rubavax Injection [At Least] 100TCID50 14 October 1994 Almevax Rubella Vaccine 1000TCID50/Dose1 2 November 1994 MSD Meruvax II Vaccine1 2 November 1994 Mumpsvax Lyophilised Powder for Injection 20000IU1 2 November 1994 Ervevax Rubella Vaccine Live EP RA 27/3 Strain 1000TCID50 2 November 1994 Pluserix MMR Vaccine Injection1 9 February 1995 Pariorix Vaccine1 20 February 1995 MSD Attenuvax Vaccine Injection [At least] 1000TCID501 24 March 1995 M-M-R II Vaccine Injection1 24 March 1995 Meruvax II Vaccine 1000 TCID50 7 April 1995 Attenuvax Injection 7 June 1995 M-M-R Vaccine Injection 1 March 1996 Mumpsvax Vaccine Injection 20000TCID50/Dose I March 1996 Priorix Vaccine Injection 4 December 1997 1Indicates that the product licence has been cancelled. Information relating to the conditions for which the products were licensed will be placed in the Library shortly.
§ Mr. Simon HughesTo ask the Secretary of State for Health what announcements have been made by his Department since 2 May 1997 relating to vaccination against mumps, measles and rubella; and on which date each of these announcements was made. [80033]
§ Ms JowellTwo announcements about measles, mumps, rubella (MMR) vaccine have been issued by the Department in the form of press releases from the then Chief Medical Officer, Sir Kenneth Calman. The first press release was issued on 12 March 1998 and stated that there was no scientific evidence to support giving measles, mumps and rubella vaccines in separate doses. The second was issued on 24 March 1998 and gave the Chief Medical Officer's conclusions following the meeting of an independent expert scientific group convened by the Medical Research Council (MRC). The group looked at the suggested link between measles, measles vaccine or MMR immunisation and either Crohn's disease or autism. Sir Kenneth said in the press release
Based on the views of the experts at the MRC meeting, and on previous material that I have studied, I have concluded there is no link between measles, measles vaccine or MMR immunisation and either Crohn's Disease or autism".Copies of the press releases are available in the Library.
§ Mr. Simon HughesTo ask the Secretary of State for Health how many suspected adverse reactions to mumps, rubella and measles vaccines there were in the last five years for which figures are available. [80034]
112W
§ Ms JowellThe available information listing the vaccines licensed since February 1987 and still current is shown in the table.
§ Ms JowellSuspected adverse reactions reports to measles, mumps and rubella (MMR) vaccine are given in the table:
Numbers of suspected adverse reactions reported to the Committee on Safety of Medicines from 1 January 1994 to 31 December 1998 for MMR vaccine in the United Kingdom Year All suspected adverse reactions (serious and non-serious) where MMR vaccine was indicated as a suspect drug Number of reports where MMR vaccine was indicated as suspect drug 1994 224 140 1995 237 129 1996 242 141 1997 331 209 1998 232 145 A report of a suspected adverse drug reaction does not necessarily mean that it was caused by the vaccine. Each report relates to one patient. Patients may have more than one suspected reaction and the number of reactions given exceeds the number of patients affected as seen above. The number of reports is variable due to retrospective reporting.