§ Mr. Simon HughesTo ask the Secretary of State for Health if he will list vaccines licensed since 1 February 1987 for mumps, measles, rubella or a combination of these indicating for each product the date on which a licence was granted, the conditions for which it was licensed and if the product licence is current. [19271]
§ Mr. MaloneThe available information listing the vaccines licensed since February 1987 and still current is as follows:
Product name Date of grant Pulserix MMR Vaccine Injection with Diluent1 17 June 1988 Immravax Measles Mumps Rubella Live Attenuated Vaccine1 18 September 1989 Measavax Vaccine Injection1 18 September 1989 Rubavax Rubella Live Vaccine1 18 September 1989 Rublin—Rubella vaccine live BP 28 February 1992 Immravax/measles, mumps and rubella vaccine live BP 18 October 1993 Rimevax measles vaccine 25 October 1993 Mevilin-L Measles Vaccine Live BP 6 January 1994 Eolarix vaccine injection 22 July 1994 Merieux measles and rubella vaccine injection 1 September 1994 Measavax vaccine 1000TCID50/dose 13 October 1994 Rubavax injection (at least) 1000TCID50 14 October 1994 Almevax Rubella Vaccine1 2 November 1994 Ervevax rubella vaccine live EP RA 27/3 strain 1000TCID50 2 November 1994 MSD Meruvax II Vaccine1 2 November 1994 Mumpsvax Lyophilised Powder for Injection 2000IU1 2 November 1994 Pluserix MMR vaccine injection 9 February 1995 Pariorix vaccine 20 February 1995 M-M-R II Vaccine Injection1 24 March 1995 MSD Attenuvax Vaccine injection (at least) 1000TCID501 24 March 1995 Meruvax II vaccine 1000TCID50 7 April 1995 Attenuvax injection 7 June 1995 M-M-R II vaccine injection 1 March 1996 Mumpsvax vacine injection 20000TCID50/dose 1 March 1996 11 Indicates that the product licence has been cancelled. Information relating to the conditions for which the products were licensed will be placed in the Library shortly.
§ Mr. HughesTo ask the Secretary of State for Health if he will list for the last five years for which information is available the serious adverse reactions to vaccines264W containing components against mumps, measles or rubella; if he will list trial products which have been withdrawn; and if he will make a statement. [19324]
§ Mr. MaloneDrug analysis prints, listing all serious suspected reactions reported to the Committee on Safety of Medicines between 1 January 1992 and 31 December 1996 for vaccines containing components against mumps, measles or rubella will be placed in the Library shortly, along with an information sheet to aid interpretation. No trial products have been withdrawn, and no licences for these vaccines have been suspended or revoked in the last five years.
I refer the hon. Member to the replies given to the hon. Member for Blaenau Gwent (Mr. Smith) on 6 November, at columns 607–11 which discusses the replacement of the urabe strain of MMR vaccine with the current strain.
§ Mr. HughesTo ask the Secretary of State for Health if he will list the dates the Committee on Safety of Medicines considered matters relating to mumps, measles and rubella vaccines which were recommended for licensing, indicating the date on which each product was considered. [19265]
§ Mr. MaloneThe available information is as follows:
Issue Considered by the Committee on Name of product Mumps 26 May 1983 Pariorix Measles 18 December 1980 Rimevax 28 July 1988 Measavax 22–23 September 1988 Immravax Rubella 26–27 September 1984 Ervevax 28 July 1988 Rubavax 22–23 September 1988 Immravax
§ Mr. HughesTo ask the Secretary of State for Health if he will list the number of suspected adverse reactions to mumps, measles and rubella vaccines for the last five years for which figures are available. [19266]
§ Mr. MaloneSuspected adverse reactions reports to measles, mumps and rubella vaccine are given in the table.
265W
Numbers of suspected adverse reactions reported to the committee on Safety of Medicines from 1 January 1992 to 31 December 1996 for MMR vaccine in the United Kingdom Year All suspected adverse reactions (serious and non-serious) where MMR vaccine was indicated as a suspect drug Number of reports where MMR vaccine was indicated as a suspect drug 1992 350 180 1993 232 129 1994 212 134 1995 228 122 1996 232 134 A report of a suspected adverse drug reaction does not necessarily mean that it was caused by the vaccine. Each report relates to one patient. Patients may have more than one suspected reaction and the number of reactions given exceeds the number of patients affected as seen above.
§ Mr. HughesTo ask the Secretary of State for Health if he will list the statements his Department has made since 1 January 1986 relating to vaccination against mumps, measles and rubella. [19269]
§ Mr. HoramFull details of the recommendations for immunisation against measles, mumps and rubella are given in the United Kingdom Health Departments' memorandum "Immunisation against Infectious Disease" which is updated regularly and was published in 1996 (ISBN: 011 321815 X), 1992 (ISBN: 0 11 321515 0), 1990 (ISBN: 0 11 321251 8), 1988 (ISBN: 0 11321136 8) and 1984 (ISBN: 0 90 2650 69 6). The following letters from the chief medical officer and circulars about measles, mumps and/or rubella have also been issued: PL/CMO(96)6, PL/CMO(94)13, PL/CMO(94)12, PL/CMO (94)10, PL/CMO(92)11, PL/CMO(88)19, PL/CMO(88)17, PL/CMO(88)16; CMO Update Numbers 8 (November 1995), 7 (October 1995) and 6 (July 1995); EL(96)61, EL(95)113, EL(94)73 and EL(94)60. Press releases about these immunisations include: 96/239, 95/361, 95/209, 95/154, 94/599, 94/433, 94/354, H92/277, 89/476, 89/353, 89/8 and 88/166. Copies of all these are available in the Library.