§ Lord Braine of Wheatleyasked Her Majesty's Government:
How many research projects using human embryos have been licensed by the Human Fertilisation and Embryology Authority since it was appointed; and
Whether they will list the research projects using human embryos which have been licensed by the Human Fertilisation and Embryology Authority since it was appointed.
§ Baroness CumberlegeThe Human Fertilisation and Embryology Authority (HFEA) assumed its full powers on 1 August 1991. Since then 44 research projects involving human embryos have been licensed. These are:
Preimplantation stage diagnosis of sickle cell anaemia and haemophilia A in the human embryo
A study of the growth requirements of cell lines derived from parts of the human blastocyst
The definition of optimum culture conditions for the culture of human preimplantation embryos in-vitro
The identification of criteria of human preimplantation embryo viability
Measurement of intracellular metabolites at fertilisation
Immunobiological investigations into human fertilisation and implantation
The definition of optimal culture conditions for the culture of human preimplantation embryos in-vitro
The development of a contraceptive vaccine
Methods for evaluating normality of pre-implantation development
Studies of methods for the cryopreservation of human oocytes
Transplantation antigen expression of human preimplantation embryos
Biopsy of human embryos for the preimplantation diagnosis of genetic disease
The use of growth factors to improve human embryo culture for in-vitro fertilisation
Assisted hatching of human IVF embryos
Partial zone dissection and sub zonal insemination for the alleviation of male infertility
A study of the mechanism for trisomy formation in man
Development of techniques and the establishing of a protocol for the microinsemination by injection of spermatozoa into the perivitelline space of oocytes
112WAIn-vitro studies of human oocytes after microinjection of spermatozoa
Growth and characterisation in-vitro of cells derived from early human conceptus
Growth requirements of the human preimplantation embryo in-vitro
In-vitro development and implantation of normal human pre-embryos and comparison with uni- or poly-nucleate pre-embryos
Evaluation of three different culture systems for human embryos
Effects of substances and procedures on the ability of human spermatozoa to penetrate zona-free hamster eggs
To measure the activity of metabolic enzymes in spare human preimplantation embryos
To measure the activity of enzymes implicated in genetic disorders
Sperm/oocyte interaction and fertilisation failure
Preimplementation genetic diagnosis parallel investigations
Development of sub zonal insemination. A technique to micro-inject sperm into oocytes as a treatment for male infertility
Micromanipulation of human gametes in the treatment of male factor infertility; comparison of partial zona dissection and sub zonal insemination
Use of co-cultures in human IVF
Release of lymphokines by the human embryo
In-vitro maturation and cryopreservation of human oocytes
Use of aged unfertilised oocytes to assess the fertilising ability of human spermatozoa
Investigation of the effects of immuno-modulatory factors on implantation in-vitro
Pre-implantation diagnosis of genetic disease
A study of fertilisation by micromanipulation
The use of human embryos to develop preimplantation diagnosis techniques
Preimplantation diagnosis of genetic disease
Development of micromanipulation-assisted IVF techniques for male factor infertility
The use of unfertilised human oocytes to assess the fertilising ability of human spermatozoa via ICSI
Comparison of ICSI and re-insemination for the fertilisation of 24 hour old unfertilised eggs
ICSI for the treatment of patients with severe male infertility
Cell biology of human spermatozoa