§ Information is not available on work supported from public funds in the universities and hospital medical schools.
402W§ Mr. Shersbyasked the Secretary of State for Education and Science if she will publish in the Official Report in tabular form details of the various dental research projects which are currently being supported from public funds, together with the name of the research establishment at which such research is being conducted, the amount of money being allocated annually to each project and the name of the researchers in charge of each project.
§ Mrs. Shirley Williams, pursuant to her reply [Official Report, 19 March 1979; Vol. 964, c. 436], gave the following information:
The Medical Research Council is supporting the projects listed below:
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Researcher Establishment Project title Duration Approximate annual allocation £
— MRC Dental Unit, Bristol The growth and development of teeth in man and other vertebrates. Ongoing 7,805 — MRC Dental Unit, Bristol The structure and function of periodontal tissues and the masticatory mechanism. Ongoing 29,495 — MRC Dental Unit, Bristol The structure, growth, metabolism and bacteriology of plaque especially in relation to dental caries. Ongoing 72,875 — MRC Dental Unit, Bristol The structure and the physical and chemical properties of normal and diseased enamel. Ongoing 36,725 Professor D. J. Anderson … Bristol University, Dental School The neurophysiology or oral structures 10 years 25,750 Miss D. A. M. Geddes … Glasgow University, Department of Oral Medicine Human dental plaque organic acid production and pH changes, related to caries and gingivitis. 2 years 3,790 Professor A. A. Grant … Manchester University, Turner Dental School Preparation and implantation studies of phosphate ceramic. 3 years 6,800 Dr. H. N. Newman … Institute of Dental Surgery, Dental School, London Dental plaque and the pathogenesis of chronic inflammatory peridontal disease. 2¾ years 3,960 Professor J. R. Garrett … King's College Medical School, London, Department of Oral Pathology. Resynthetic process in mucosubance-secreting salivary cells. 3 years 6,900 Professor A. E. W. Miles … London Hospital Medical College, Department of Oral Pathology. Behaviour of oral mucosa in organ culture and its reaction to products of the inflammatory 3 years 10,340 Dr. L. H. Smaje … Charing Cross Hospital Medical School, London, Department of Physiology. Microvascular flow and transport in the submandibular salivary gland. 3 years 12,630 Dr. C. Robinson … Leeds University, Department of Oral Biology Relationship between histological appearance and composition of the enamel organ and associated developing enamel. 3 years 5,850 Professor J. Dobbing … Manchester University, Department of Child Health. The effect of in-utero, birth and neo-natal events on tooth development in man. 3 years 5,070 Dr. B. K. B. Berkovitz … Bristol University, Department of Anatomy An autoradiographic and E-M study of the peridontal ligament following changes in its eruptive and functional state. 3 years 10,300 Dr. C. Robinson … Leeds University, Department of Oral Biology Amino acid analysis of protein samples from dental hard tissues. 1 year 10,000 Dr. J. A. Sofaer … Edinburgh University, Department of Oral Medicine and Oral Pathology. Morphogenetic influences and patterns of developmental stability in the mouse vertebral column. 3 years 3,730 Professor A. Dolby … Welsh National School of Medicine, Cardiff, Department of Periodontology. The nature of pemphigus antigen 3 years 1,800 Dr. S. Pauline Handley … Manchester University, Department of Bacteriology and Virology. The incidence, fine structure, properties and role in adherence of fimbriae on oral streptococci. 3 years 5,000 406W407W
Researcher Establishment Project title Duration Approximate annual allocation £
Professor C. J. Smith … Sheffield University, Department of Oral Pathology Morphometric and steriological analysis of normal and pathological human oral mucosa. 3 years 13,171 Professor J. H. Wolstencroft … Birmingham University, Department of Physiology The control of noxious input of trigeminal origin by the raphe nuclei. 3 years 6,160 Professor B. Cohen … Royal College of Surgeons of England, London Department of Dental Science. Immune responses to the microbial flora of dental plaque: their relationship to development of peridontal disease. 3 years 8,860 Professor P M. C. James … Birmingham University, Department of Denta Health. Oral conditions in relation to trace elements in human tissue and the environment. 3 years 1,580 Dr. R. W. A. Linden … Guy's Hospita. Medical School, London. Department of Physiology. Investigation into the effects of sympathetic efferent activity on dental mechanoreceptor afferent discharge. 3 years 16,900 Dr. R. Stephens … Birmingham University, Department of Chemistry Pilot study of tooth lead levels 2 years 3,660 Dr. G. Embery … Liverpool University, Department of Dental Sciences. Origin and role of anionic macromolecules in the structure and function of dental plaque and calculus. 3 years 4,700 Professor M. Braden … London Hospital Medical College, Department of Materials Science in Dentistry. Developments of new elastomeric prosthetic materials. 2 years 4,420 Dr. M L. Hayes … Bristol University Department of Biochemistry Possible use of medium chain fatty acids to prevent dental caries. 3 years 4,216 Dr D. F. Williams … Liverpoo University Department of Den a Sciences. The interactions between biomaterials and tissues especially in relation to dental and oral surgery. 3 years 12,330 Dr J. E. Eastoe … Royal College of Surgeons of England. London Department of Dental Sciences. Nitrogenous metabolites of micro-organisms in dental plaque. 1½ years 5,300 Professor A. J. Darling … Britsol University, Department of Dental Medicine Collagen fibre crimping in the periodontal membrane and its potential role in tooth eruption, support and movement. 3 years 7,060 Dr J. J. Reynolds … Strangeways Research Laboratory Cambridge, Department of Cell Physiology Control mechanisms in craniotacial suture gowth and remodelling; the biological basis for orthodontic treatment 3 years 8,440 408W409W
Researcher Establishment Project title Duration Approximate annual allocation £
Professor R. Duckworth … London Hospital Medical College, Department of Oral Medicine and Periodontology. The prevention of dental disease in children by frequent prophylaxes. 3½ years 11,180 Professor T. Lehner … Guy's Hospital Medical School, London, Department of Oral Immunology and Microbiology. Oral disease in immunodeficient children 3 years 6,600 Dr. R. C. Paterson … Guy's Hospital Medical School, London, Department of Conservative Dental Surgery. Caries, materials, bacteria and pulp response 3 years 6,930 Dr. D. M. Walker … Welsh National School of Medicine, Cardiff, Department of Oral Medicine and Oral Pathology. The functional properties of the gingival infiltrate in patients with periodontal disease. 3 years 3,420 Dr. G. Colman … Royal College of Surgeons of England, London, Dental Research Unit (Downe, Kent). The modification of the microbial flora of the dental plaque by trace elements. 3 years 10,670 Dr. Ludmila Ivanyi … Institute of Dental Surgery, London, Department of Oral Medicine. T-suppressor cells in the regulation of cell-mediated immunity to plaque antigens in periodontal disease in man. 3 years 12,000 Mr. I. S. Beattie … Edinburgh University, Department of Veterinary Studies. Improvement and expansion of faculty electron microscope facility. 1 year 6,000 Professor N. W. Johnson … London Hospital Medical College, Department of Oral Pathology. Ultrastructural and microanalytical studies of the mechanisms of oral disease and of their prevention and treatment. 3 years 3,000 Dr. J. S. Johnson … Manchester University, Department of Orthodontics. Development of computer-graphic programmes in the mathematical analysis of the skull cephalostat radiograph. 3 years 3,360 Professor D. Vudilevich … Queen Elizabeth College, London, Department of Physiology. Carrier-mediated transport of amino acids, sugars and other substances in the in situ cat subman-dibular gland. 2 years 4,700 Professor T. Lehner … Guy's Hospital Medical School, London, Department of Oral Immunology and Microbiology. Central and peripheral immunological control in the prevention of dental caries. 3 years 7,740 I understand from my right hon. Friend the Secretary of State for Social Services that his Department is supporting the projects listed below:
Researcher Establishment Project title Duration Expected completion Total cost £
Professor Hardwick Manchester university Effect of fluoridation on children's teeth 4 years 31 March 1979 3,200 Professor Winter and Dr. Murray Eastman dental hospital An evaluation of the utilisation and cost effectiveness of dental auxiliaries in the National Health Service 2 years 31 March 1979 12,600 Professor James Birmingham university National survey of adult dental health 1978 2 years October 1979 34,600 Professor Emslie and Professor Naylor Guys hospital, London Thamesmead dental health project—A study of treatment patterns provided to a community receiving regular dental care at a health centre, specifically oriented towards prevention of dental disease 5 years 30 September 1982 69,200 Professor Cohen Royal College of Surgeons Research into the reduction of dental caries by immunisation 10 years 1980 515,000